• Three Myths of Medical Cannabis
  • Unleash Your Vet’s Voice
  • Visit Us at Pet Expo April 27-29 in OC

Three Myths of Medical Cannabis for Dogs

Don’t Get Fooled Again

#1 Weight, Wait, What?

We’ve been formulating custom right:ratio for dogs for two years and have treated over 22 breeds, +240 dogs and made over 450 unique formulae. While weight is a factor in developing proper ratios, potency and recommended usage, many other factors are equally importantnot to mention ratios of key cannabinoids to each other, as in the human realm. Specifically, our data and experience have revealed that often, breed and age are as — if not more — important than weight in determining how to ensure the most efficacious deployment of medical cannabis for cancer, arthritis, seizures or severe anxiety.
For example, we’ve seen Chihuahuas require +>4 mg/ml of THCd-9 for adequate therapeutic dosing without manifesting any signs of psychoactivity. Conversely, more than one Akita over 75 pounds has an established therapeutic dose of right:ratio with THCd-9 below 1.75 mg/ml. Factor in age — where younger dogs tend to benefit from higher potencies of medical cannabis — and often, a two year old small dog may be getting three or four times more cannabinoids, including THCd-9, than certain older, larger breeds.
This is not surprising to us because it has been noted in very recent human data that cannabis dosing requires careful and precise dosing. More is NOT always better:

“In a study of 263 opioid-treated cancer patients with poorly controlled pain, the group receiving 21 mg of combined THC and CBD each day experienced significant improvements in pain levels, more so than the group that received 52 mg daily.”

Finally, we always ask our clients what the desired benefits of right:ratio they’re seeking for their pet. Often, clients want to address “Cancer / pain / anxiety” which is a tall order in one medicine. In such cases, we often seek clarification of the primary medical issues and then formulate not just on weight, but taking into account a variety of factors including breed, age, co-morbidity, concurrent medications and goals for treatment.

#2 Safe for Humans Means Safe for Dogs

At right:ratio, we pour over third-party laboratory results called Certificates of Analysis (“COAs”) for fun, and spend a lot of time doing it. We’re not masochists but have found data that justifies our magnifying glass approach to each test of cannabis that might be used for dogs. The reason is that even though a particular COA may show that the cannabis concerned meets available limits for pesticides and would be deemed safe for humans, certain pesticides are more toxic for dogs. As a result, even miniscule amounts, less than 1.5 parts per million, will cause us to reject a product that all 29 states with medical or recreational cannabis laws would approve as safe for humans to consume.
This is complicated by the fact that there is no federal register of what pesticides might be safe to use on cannabis. In fact, California’s own Department of Pesticide Regulation “does not publish a list of products for use on cannabis.” We’re not the only ones concerned either.
The myth that human safety equates to canine safety couldn’t be more dangerous when it comes to human edibles made for either medical or recreational consumption in California. In our experience, there is no human edible product like snacks or sweets that should ever be given to a dog, regardless of its designation as a medical cannabis product for a human. The perils of this are great, from cannabis toxicity, including severe sedation/lethargy, dilated pupils or glassed over eyes, dazed expression, urinary incontinence, difficulty walking and vomiting.
Our Advisory Board (one veterinarian specialist and one cancer specialist) diligently reviews a wide array of publications and data to ensure that any products used in cannabis production or extractions that we use for right:ratio are safe for pets, regardless of their status for humans.

#3 All Dogs Can Tolerate Medical Cannabis

While many in the cannabis community believe that the plant may cure a huge variety of ailments, we at right:ratio focus on cancer, arthritis, severe
anxiety and seizures as conditions we believe for which medical cannabis has genuine efficacy.

It is not always true, however, that every dog can safely use medical cannabis. Dogs with liver or heart disease may require a dose reduction or a change in ratio. In cases where the disease is severe enough, we may feel the risk of using cannabis outweighs the benefit and decline treatment.

MDR1 Gene/Mutuation

Another consideration when creating a formula is knowing the breed of the pet. This can be important because, for example, herding breeds are known to possess a genetic mutation in a specific gene called ABCB1/MDR1 gene — which may impact the absorption, distribution and excretion of certain drugs. Because of the mutation, these breeds can be susceptible to severe drug toxicity. The mutation inhibits the transport pump (P-glycoprotein) which may further lower the excretion rate of certain drugs.

The best first step is to identify whether your dog may be among the breeds with the MDR1 mutation before embarking on medical cannabis. Fortunately, the Washington State University Veterinarian School offers low cost saliva tests that many of our customers pets undergo before ordering right:ratio.

Impact on Drug Metabolism

Lastly, certain doses of CBD can inhibit an important enzyme called Cytochrome P450 that assists in the metabolism of specific drugs. We at right ratio carefully review the medications your pet is on (via our intake form) to confirm there are no obvious drug interactions before providing custom medical cannabis for your pet.

Unleash Your Vet’s Voice on Medical Cannabis

Support New Legislation to Enable Veterinarians to Participate in the Medical Cannabis for Pets Discussion – Click Here

The New MMIC Requirement for Tax Relief for Medical Cannabis

Visit Us at our Booth at Pet Expo April 27-29, 2018

Our month’s favorites of Moose (in memoriam)…